Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors during the central anxious process, conolidine modulates alternate molecular targets. A Science Improvements analyze found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabilit... https://whatisproleviate43086.webbuzzfeed.com/38207939/alternative-natural-pain-relief-to-replace-traditional-painkillers-options